Satellite symposia - Monday 16th of October

14.00 – 16.00  Symposium: Microbiota in respiration and cardiovascular disease,
 Karolinska  Respitationand Circulation Network (KIRCNET)

Satellite symposia - Tuesday 17th of October

09.00 – 17.00 Autumn school: The expanding tool box of immunological techniques
12.45 – 17.00 The symposium of the Scandinavian Network for Immunotherapy of Cancer (SNIC)
14.00 – 16.00  Symposium: Innate Immunity in Cancer and Tissue DamageNordic Complement Committee

SSI2017 - Conference Programme

Tuesday 17th of October

18.45 – 21.00  SSI2017 Welcome reception 

Welcome to the magnificent Stockholm City Hall, one of Sweden´s most famous buildings, and one of the capital´s most visited tourist attractions. It is famous for its grand ceremonial halls and unique art pieces and is the venue of the Nobel Prize banquet held on 10th of December each year. 
Stockholm City Hall is hosted by The City of Stockholm and the Stockholm County Council
*Pre-registration required*

Wednesday 18th of October - Conference Programme

08.30 – 10.15  Session 1: Innate immunity and the immune environment I

Chairs Ann-Charlotte Wikström, Karolinska Institutet, Sweden
Ulf Yrlid, Gothenburg University, Sweden
08.30 - 08.55 Alberto Mantovani, Humanitas Research Hospital Milan, Italy
The interplay between cellular and humoral innate immunity in defence and tissue repair
09.00 – 09.25 Nelson Gekara, Umeå University, Sweden
DNA damage signaling in innate immunity
09.30 – 09.40 Waltraud Schrottmaier, Umeå University, Sweden
Activation of circulating platelets leads to innate-like delivery of potent antiviral antibodies
09.45 – 09.55 Ebba Sohlberg, Karolinska Institutet, Sweden
Profound NK cell differentiation block in a subgroup of neutropenic patients
10.00 – 10.10 Minghui He, Karolinska Institutet, Sweden
B cells expressing overactive WASp in X-linked neutropenia show decreased germinal center formation and increased plasma cell differentiation
10:15 - 10:45 Coffee break

10.45 – 12.30  Session 2: Innate immunity and the immune environment II

Chairs Mattias Forsell, Umeå University, Sweden
Jóna Freysdóttir,  University of Iceland, Iceland
10.45 – 11.10 Mathias Hornef, University of Aachen, Germany
Ontogeny of the innate host response to intestinal infection
11.15 – 11.40 Giuseppe Matarese, University of Naples Federico II, Italy
Metabolic control of immune tolerance
11.45 – 11.55 Kerstin Wendland, Lund University, Sweden
The role of retinoic acid signaling in thymic function
12.00 – 12.10 Sara Martina Parigi, Karolinska Institutet, Sweden
Crosstalk between innate lymphoid cells and T cells enhances IL-22 production
12.15 – 12.25 Rubin Joshi, Karolinska Institutet, Sweden
Human regulatory T cells suppress CD4+ T cells by rapidly altering the phosphoproteome
12.30 – 14.00 Lunch (90 min)
13.15 - 13.55 Cutting-edge lunch seminar
Alexander Scheffold, Charité Berlin, Germany
Human antigen specific regulatory T cells mediate tolerance against aeroantigens
*Provided by Miltenyi Biotec*
13.00 - 14.00 SSI council meeting (SSI board members only)

14.00 – 15.00  Session 3: Basic Immunology 1

Chairs Lill Mårtensson-Bopp, Gothenburg University, Sweden
Mikael Sigvardsson, Linköping University, Sweden
14.00 – 14.25 Daniel M Davis, University of Manchester, UK. Using super-resolution microscopy to watch immune cells kill
14.30 – 14.40 Christopher Sundling, Gavan Institute of Medical Research, Australia
Counter-selection versus switching in the demise of IgM+ germinal center B cells
14.45 – 14.55 Natasja Wulff Pedersen, Denmark Technical University, Denmark
Automated identification of MHC multimer-binding T cells
15.00 – 15.45 Coffee break (45 min)
15.15 - 15.35 Sponsor seminar I - Stemcell Technologies
Bruno Zaragoza
PhD, Field Application Scientist, Europe
Fast and Easy Isolation of Rare Immune Cells

15:45 – 16.45  Session 4: Tumor Immunology I

Chairs Mikael Karlsson, Karolinska Institutet, Sweden
Susanna Cardell, Gothenburg University, Sweden
15.45 – 16.10 Padmanee Sharma, MD Andersson Cancer Center, USA
From the clinic to the lab: Investigating response and resistance mechanisms to immune checkpoint therapy
*2017 Nordic Foundation speaker*
16.15 – 16.25 Marit Inngjerdingen, Oslo University Hospital, Norway
Resistance of T cell acute lymphoblastic leukemia to autologous rat NK cells is reversed by IL-12, IL-15, and IL-18
16.30 – 16.40 Tanja Lövgren, Uppsala University, Sweden
Immunological biomarkers correlate to survival in CAR19-treated patients
16.45 – 18.15 Poster viewing
17.15 – 19.15 SJI Editorial Board Meeting (by special invitation)
18.15 - Free evening activities

Keynote speakers

Alberto Mantovani, Humanitas Research Hospital Milan, Italy

Daniel M Davis, University of Manchester, UK

Nelson Gekara, Umeå University, Sweden

Padma Sharma, MD Andersson Cancer Center, USA

Mathias Hornef, University of Aachen, Germany
Giuseppe Matarese, University of Naples Federico II, Italy

Thursday 19th October

08.30 – 10.15  Session 5: Tumor Immunology II

Chairs Andreas Lundqvist, Karolinska Institutet, Sweden
Kristina Lejon, Umeå University, Sweden
08.30 - 08.55 Gunnar Pejler, Stockholm University, Sweden.
The role of mast cells and their proteases in melanoma
09.00 - 09.25 Nathaniel West, Genetech, USA
The OSM-stromal cell axis in gut inflammation
09.30 – 09.40 Paulina Akeus, Gothenburg University, Sweden
Depletion of Treg promotes chemokine production and accumulation of CXCR3+ T cells in intestinal tumors
09.45 – 09.55 Kristina Witt, Karolinska Institutet, Sweden
Cripto-1 vaccination elicits protective immune response to metastatic breast cancer and breast CSC
10:00 - 10:45 Coffee break (45 min)
10.15 - 10.35 Sponsor seminar II - BD
Enabling deep scientific insights with High-Parameter Solutions

Sara Johansson, Ph.D. Technical Sales Specialist, BD Biosciences

10.45 - 12.30  Session 6: Basic Immunology II

Chairs Seppo Meri, University of Helsinki, Finland
Karin Loré, Karolinska Institutet, Sweden
10.45 – 11.10 Gunilla Karlsson Hedestam, Karolinska Institutet, Sweden
Allelic diversity of human immunoglobulin germline genes 
11.15 – 11.25 Christian Pou, Karolinska Institutet, Sweden
Maternal antibodies against all human viruses monitored longitudinally in human newborns
11.30 – 11.40 Sophia Björkander, Stockholm University, Sweden
EBV-latency accelerates the decay of childhood vaccine responses
11.45 – 11.55 Silke Sohn, Karolinska Institutet, Sweden
Scavenger receptor regulation of macrophage polarization.
12.00 – 12.10 Raine Toivonen, University of Turku, Finland
Gut dysbiosis induces dendritic-cell traffic from colon to pancreatic
lymph node: implications for activation of islet-reactive T cells in type 1 diabetes

12.15 - 13.45 Lunch (90 min)
12.45 – 13.45 SSI General Assembly (for all SSI members)

13.45 – 14.45   Session 7:  Autoimmunity I

Chairs Anne Spurkland, University of Olso, Norway
Fredrik Wermeling, Karolinska Institutet, Sweden
13.45 – 14.10 Ken Smith, University of Cambridge, UK.
Predicting and explaining long-term outcome in autoimmune and inflammatory disease.
14.15 – 14.25 Harald Lund, Karolinska Institutet, Sweden
TGF-beta defines microglia and monocyte function in the central nervous system.
14.30 – 14.40 Ramil Hakim, Karolinska Institutet, Sweden
Histocompatibility of mouse bone marrow-derived mesenchymal stem cells transplanted into experimental spinal cord injury causes polarization of microglia towards the M2 phenotype and improved functional recovery.
14.45 – 15.30 Coffee (45 min)
15.00 - 15.20 Sponsor seminar III - Agilent Technologies
Lars Martlev,  Agilent Technologies.​​​​​​​
Measure Immune Cell Activation in Minutes – in real-time


15.30 – 17.00  Session 8: Autoimmunity II

Chairs Silke Appel, University of Bergen, Norway
Sandra Kleinau, Uppsala University, Sweden
15.30 – 15.55 Jan Rehwinkel, University of Oxford, UK
Sensing and Restricting: Innate Immune Control of Virus Infection
16.00 – 16.25 Peder Olofsson, Karolinska Instituet, Sweden
Bioelectronic medicine in regulation of inflammation and treatment of inflammatory disease
16.30 - 16.40 Jonathan Coquet, Karolinska institutet, Sweden
Establishing the requirements for robust Th2 immunity in asthma.
16.45 – 16.55 Mattias Magnusson, Linköping University, Sweden
CTLA-4 mediates IDO- and Treg-dependent protection against antigen-induced arthritis induced by IFN-alpha
17.00 – 18.30 Poster viewing
19.30 – 23.00 Conference party at Clarion Sign Hotel (ticket required)

Gunnar Pejler, Stockholm University, Sweden.

Jan Rehwinkel

University of Oxford, UK

Bill Murphy, UC Davis, USA

Nathaniel West,
Genetech, US


Peder Olofsson 
Karolinska Institutet, Sweden

Johanna Olweus 
University of Oslo, Norway

Gunilla Karlsson Hedestam, Karolinska Institutet, Sweden

Fredrik Piehl 
Karolinska Institutet, Sweden

Shannon Maude, Childrens hospital of Philadelphia, USA

Ken Smith, University of Cambridge, UK

Anna Villa
Ospedale San Raffaele Milan, Italy

Friday 20th October

08.30 – 10.15  Session 9  Immunotherapy I

Chairs Trevor Owens, University of Southern Denmark, Denmark
Marianne Quiding-Järbrink, University of Gothenburg, Sweden
08.30 - 08.55 Fredrik Piehl, Karolinska Institutet, Sweden
B-cell depletion in neurological autoimmune disease.
09.00 – 09.25 Anna Villa, Ospedale San Raffaele, Milan, Italy
Platelet defect in Wiskott Aldrich Syndrome: new insights from mouse model and patients.
09.30 – 09.40 Di Yu, Uppsala University, Sweden
Adenovirus, Semliki Forest virus and vaccinia virus-induced immunogenic cell death augments oncolytic virus immunotherapy.
09.45 – 09.55 Jonas Nilsson, University of Gothenburg, Sweden
Clinical responses to adoptive T-cell transfer can be modeled in PDXv2.0 - a novel autologous immune-humanized melanoma mouse model
10.00 – 10.10 Sharesta Khoenkhoen, Karolinska Institutet, Sweden
IκBNS-deficiency attenuates TACI function and impairs Pax5 downregulation during plasma cell differentiation
10:15 - 10:45 Coffee break (15 min)

10.45 – 12.15  Session 10:  Immunotherapy II

Chairs Anders Örn, Karolinska Institutet, Sweden
Magnus Essand, Uppsala University, Sweden
10.45 – 11.10 Bill Murphy, UC Davis, USA.
What goes up must come down: immune system dynamics impacting cancer immunotherapy
11.15 – 11.40 Johanna Olweus, University of Oslo, Norway
T-cell Immunotherapy of cancer
11.45 - 12.10 Shannon Maude, Childrens hospital of Philadelphia, USA
Harnessing the cytotoxicity of T cells to treat acute lymphoblastic leukemia
*2017 IMTAC speaker*
12.15 – 14.00 End of meeting and lunch   

SSI 2018
Next year the SSI annual meeting is within the ECI meeting and we are happy to welcome you all to Amsterdam 2nd to 5th  of September 2018.